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Published in 2023 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.27111
Abstract: A newly synthesized small molecule, KTT‐1, exhibits kinetically selective inhibition of histone deacetylase 2, HDAC2, over its homologous enzyme, HDAC1. KTT‐1 is hard to be released from the HDAC2/KTT‐1 complex, compared to the HDAC1/KTT‐1 complex…
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Keywords:
ktt;
selectivity;
hdac1;
hdac2 ... See more keywords