Kinetic proofreading of lipochitooligosaccharides determines signal activation of symbiotic plant receptors
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2111031118
Abstract: Significance Plant cell surface receptors perceive carbohydrate signaling molecules and hereby establish communication with surrounding microbes. Genetic studies have identified two different classes of lysin motif receptor kinases as gatekeepers that together trigger the symbiotic… read more here.
Keywords: lco; activation; kinetic proofreading; activation symbiotic ... See more keywords
Pioneer transcription factors in chromatin remodeling: The kinetic proofreading view.
Sign Up to like & getrecommendations! Published in 2020 at "Physical Review E"
DOI: 10.1103/physreve.101.040401
Abstract: Pioneer transcription factors are a recently defined class of transcription factors which can bind directly to nucleosomal DNA; they play a key role in gene activation in certain pathways. Here we quantify their role in… read more here.
Keywords: pioneer transcription; transcription; chromatin remodeling; kinetic proofreading ... See more keywords
Histone mark recognition controls nucleosome translocation via a kinetic proofreading mechanism: Confronting theory and high-throughput experiments.
Sign Up to like & getrecommendations! Published in 2019 at "Physical review. E"
DOI: 10.1103/physreve.99.060401
Abstract: Chromatin remodelers are multidomain enzymatic motor complexes that displace nucleosomes along DNA and hence "remodel chromatin structure," i.e., they dynamically reorganize nucleosome positions in both gene activation and gene repression. Recently, experimental insights from structural… read more here.
Keywords: chromatin; mark recognition; histone mark; kinetic proofreading ... See more keywords
A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aau5721
Abstract: Organized for action It is becoming increasingly clear that biomolecular condensates, which are concentrations of macromolecules not surrounded by a membrane, are a key organizational structure in eukaryotic cells (see the Perspective by Martin and… read more here.
Keywords: phase transition; time; kinetic proofreading; activation ... See more keywords
Kinetic Proofreading.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-040320-103630
Abstract: Biochemistry and molecular biology rely on the recognition of structural complementarity between molecules. Molecular interactions must be both quickly reversible, i.e., tenuous, and specific. How the cell reconciles these conflicting demands is the subject of… read more here.
Keywords: kinetic proofreading; thermodynamics; biochemistry; biology ... See more keywords
Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.42475
Abstract: The immune system distinguishes between self and foreign antigens. The kinetic proofreading (KPR) model proposes that T cells discriminate self from foreign ligands by the different ligand binding half-lives to the T cell receptor (TCR).… read more here.
Keywords: tcr; optogenetic control; kinetic proofreading; cell receptor ... See more keywords