Designing Thermally Safe Operation Conditions for Isoperibolic Liquid–Liquid Semibatch Reactors without Kinetic and Solubility Parameters: I. Development of the Procedure for Kinetically Controlled Reactions
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DOI: 10.1021/acs.iecr.7b02599
Abstract: In the fine and pharmaceutical chemical industries, designing thermally safe operating conditions for liquid–liquid semibatch reactors (SBRs) is a very important issue to prevent the occurrence of thermal runaway. However, because of the time and… read more here.
Keywords: kinetic solubility; designing thermally; solubility parameters; liquid liquid ... See more keywords
Effect of Extent of Supersaturation on the Evolution of Kinetic Solubility Profiles.
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DOI: 10.1021/acs.molpharmaceut.6b00788
Abstract: Solubility limited compounds require enabling formulations such as amorphous solid dispersions (ASDs) to increase the apparent solubility by dissolving to a concentration higher than the equilibrium solubility of the drug. This may lead to subsequent… read more here.
Keywords: kinetic solubility; extent supersaturation; solubility profiles; precipitation ... See more keywords
Lyophilization of Curcumin–Albumin Nanoplex with Sucrose as Cryoprotectant: Aqueous Reconstitution, Dissolution, Kinetic Solubility, and Physicochemical Stability
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911731
Abstract: An amorphous curcumin (CUR) and bovine serum albumin (BSA) nanoparticle complex (nanoplex) was previously developed as a promising anticancer nanotherapy. The CUR-BSA nanoplex had been characterized in its aqueous suspension form. The present work developed… read more here.
Keywords: dissolution; cur; kinetic solubility; aqueous reconstitution ... See more keywords