The kinetoplast DNA of the Australian trypanosome, Trypanosoma copemani, shares features with Trypanosoma cruzi and Trypanosoma lewisi.
Sign Up to like & getrecommendations! Published in 2018 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2018.02.006
Abstract: Kinetoplast DNA (kDNA) is the mitochondrial genome of trypanosomatids. It consists of a few dozen maxicircles and several thousand minicircles, all catenated topologically to form a two-dimensional DNA network. Minicircles are heterogeneous in size and… read more here.
Keywords: kinetoplast dna; trypanosoma copemani; lewisi; trypanosoma ... See more keywords
Estimating properties of kinetoplast DNA by fragmentation reactions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Physics A: Mathematical and Theoretical"
DOI: 10.1088/1751-8121/aaf15f
Abstract: The mitochondrial DNA of trypanosomes, called kinetoplast DNA (kDNA) contains thousands of minicircles that are topologically linked into a single structure that resembles a medieval chainmail. This biological chainmail is characterized by two parameters: the… read more here.
Keywords: kinetoplast dna; network; density; valence ... See more keywords
Leishmania kinetoplast DNA contributes to parasite burden in infected macrophages: Critical role of the cGAS-STING-TBK1 signaling pathway in macrophage parasitemia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1007070
Abstract: Leishmania parasites harbor a unique network of circular DNA known as kinetoplast DNA (kDNA). The role of kDNA in leishmania infections is poorly understood. Herein, we show that kDNA delivery to the cytosol of Leishmania… read more here.
Keywords: sting tbk1; dna; kinetoplast dna; leishmania ... See more keywords