KIR3DL2 contributes to the typing of acute-type adult T-cell leukemia and is a potential therapeutic target.
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2022016765
Abstract: Adult T-cell leukemia (ATL) is a lymphoid neoplasm caused by HTLV-1, that encodes the transcriptional activator Tax, which participates in the immortalization of infected T cells. ATL is classified into four subtypes (ie, smoldering, chronic,… read more here.
Keywords: kir3dl2; cell; atl; acute type ... See more keywords
Abundant CpG-sequences in human genomes inhibit KIR3DL2-expressing NK cells
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.12258
Abstract: Killer Immunoglobulin-like Receptors (KIR) comprise a diverse, highly polymorphic family of cell-surface glycoproteins that are principally expressed by Natural Killer (NK) cells. These innate immune lymphocytes fulfill vital functions in human reproduction and immune responses… read more here.
Keywords: dna sequences; dna; kir3dl2; cpg dna ... See more keywords