Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates
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DOI: 10.3389/fimmu.2019.00024
Abstract: Natural killer (NK) cell functions are modulated by polymorphic killer cell immunoglobulin-like receptors (KIR). Among 13 human KIR genes, which vary by presence and copy number, KIR3DL3 is ubiquitously present in every individual across diverse… read more here.
Keywords: kir3dl3; ligand function; heterozygosity; conservation extensive ... See more keywords