Placental protein expression of kisspeptin-1 (KISS1) and the kisspeptin-1 receptor (KISS1R) in pregnancy complicated by diabetes mellitus or preeclampsia
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-019-05408-1
Abstract: Purpose Kisspeptins regulate the trophoblast invasion. The disturbance of this process might lead to the development of preeclampsia (PE). Diabetes mellitus (DM) is associated with the high rate of this complication. The main hypothesis was… read more here.
Keywords: protein expression; placental protein; kiss1; expression kisspeptin ... See more keywords
MiR-199-3p modulates the onset of puberty in rodents probably by regulating the expression of Kiss1 via the p38 MAPK pathway
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.110994
Abstract: The Kiss1 gene plays an indispensable role in modulating the onset of puberty and fertility in mammals. Although an increasing number of genetic and environmental factors that influence reproduction through Kiss1 have been identified, the… read more here.
Keywords: kiss1; p38 mapk; expression; expression kiss1 ... See more keywords
Kisspeptin deficiency leads to abnormal adrenal glands and excess steroid hormone secretion.
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DOI: 10.1093/hmg/ddaa215
Abstract: Knockout mice for the kisspeptin receptor, Kiss1r, (Kiss1r-/-) and its ligand kisspeptin, Kiss1, (Kiss1-/-) replicate the phenotype of isolated hypogonadotropic hypogonadism (IHH) associated with variants of these genes in humans. A recent report suggests that… read more here.
Keywords: kiss1; steroid hormone; mice; hormone secretion ... See more keywords
Testosterone supplementation rescues spermatogenesis and in vitro fertilizing ability of sperm in Kiss1 knockout mice.
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DOI: 10.1210/endocr/bqaa092
Abstract: Restoration of spermatogenesis and fertility is a major issue to be solved in male mammals with hypogonadotropic hypogonadism. Kiss1 knockout (KO) male mice are postulated to be a suitable animal model to investigate if hormonal… read more here.
Keywords: kiss1; spermatogenesis; testosterone supplementation; mice ... See more keywords
Increased serum levels of KiSS1-derived peptides in non-small cell lung cancer patient liquid biopsies and biological relevance
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DOI: 10.21037/tlcr-22-52
Abstract: Background The secreted products of the metastasis suppressor gene KiSS1 may represent useful biomarkers in non-small cell lung cancer (NSCLC) but their levels in patients have remained poorly investigated. We previously found that forced expression… read more here.
Keywords: lung cancer; cell; kiss1 derived; kiss1 ... See more keywords
Reversibility and safety of KISS1 metastasis suppressor gene vaccine in immunocastration of ram lambs
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DOI: 10.5713/ajas.17.0629
Abstract: Objective The aim of this study was to investigate the reversibility and safety of KISS1 metastasis suppressor (KISS1) gene vaccine in immunocastration. Methods Six eight-week old ram lambs were randomly divided into vaccinated and control… read more here.
Keywords: kiss1; gene vaccine; ram lambs; primary immunization ... See more keywords