Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-018-08046-4
Abstract: Central estrogen signaling coordinates energy expenditure, reproduction, and in concert with peripheral estrogen impacts skeletal homeostasis in females. Here, we ablate estrogen receptor alpha (ERĪ±) in the medial basal hypothalamus and find a robust bone… read more here.
Keywords: kiss1 neurons; sex dependent; estrogen; bone ... See more keywords
SUN-200 Computational Model for Energy Sensing of PMv Neuronal Circuitry
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-sun-200
Abstract: Abstract The energy sensing in reproduction is mainly modulated by the ventral premammillary nucleus (PMv) neurons in hypothalamus. They are sensitive to the adipocyte-derived hormone leptin; some of them are excitatory to leptin, and the… read more here.
Keywords: kiss1 neurons; energy sensing; dat neurons; pmv ... See more keywords
The molecular phenotype of kisspeptin neurons in the medial amygdala of female mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1093592
Abstract: Reproduction is regulated through the hypothalamic-pituitary-gonadal (HPG) axis, largely via the action of kisspeptin neurons in the hypothalamus. Importantly, Kiss1 neurons have been identified in other brain regions, including the medial amygdala (MeA). Though the… read more here.
Keywords: kiss1 neurons; mea kiss1; kisspeptin neurons; medial amygdala ... See more keywords