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   Articles with "kisspeptin" as a keyword



Kisspeptin 10 Inhibited the Proliferation, Migration, and Stemness of Esophageal Cancer Cells via Regulating the SIX1/Wnt/β‐Catetin Signaling

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recommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.70244

Abstract: Esophageal cancer (EC) treatment remains challenging due to the disease's aggressive nature, frequent late‐stage diagnosis, and the need for effective multimodal therapies with minimal side effects. Kisspeptin‐10, a naturally occurring neuropeptide and known GPR54 agonist,… read more here.

Keywords: cancer; six1 wnt; migration; migration stemness ... See more keywords

Administration of Exogenous Kisspeptin Induces Breeding Competence in Post‐pubertal Female Common Carp (Cyprinus carpio)

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recommendations! Published in 2025 at "Molecular Reproduction and Development"

DOI: 10.1002/mrd.70037

Abstract: Puberty is a crucial stage in vertebrates, controlled by complex neuroendocrine mechanisms, yet its precise pathways remain unclear. Kisspeptin and melatonin are central to this regulation, acting as opposing forces: kisspeptin activates the hypothalamic‐pituitary‐gonadal (HPG)… read more here.

Keywords: common carp; cyprinus carpio; carp cyprinus; female common ... See more keywords

Short-term changes and correlations of plasma spexin, kisspeptin, and galanin levels after laparoscopic sleeve gastrectomy

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recommendations! Published in 2021 at "Surgery Today"

DOI: 10.1007/s00595-021-02240-6

Abstract: Purpose To determine the circulating levels of spexin, kisspeptin, galanin, and the correlations between these peptides after laparoscopic sleeve gastrectomy (LSG). Methods The plasma levels of the spexin, kisspeptin, and galanin and metabolic parameters (body… read more here.

Keywords: kisspeptin; galanin levels; kisspeptin galanin; spexin kisspeptin ... See more keywords

Intraperitoneal Treatment of Kisspeptin Suppresses Appetite and Energy Expenditure and Alters Gastrointestinal Hormones in Mice

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recommendations! Published in 2019 at "Digestive Diseases and Sciences"

DOI: 10.1007/s10620-019-05950-7

Abstract: Kisspeptin is a neuropeptide that plays an integral role in the regulation of energy intake and reproduction by acting centrally on the hypothalamus–pituitary–gonadal axis. Our current study explores for the first time the effects of… read more here.

Keywords: energy expenditure; energy; kisspeptin; intraperitoneal treatment ... See more keywords

Does kisspeptin act as a neuropeptide or as an adipokine in obese people?

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recommendations! Published in 2022 at "Journal of Taibah University Medical Sciences"

DOI: 10.1016/j.jtumed.2021.07.010

Abstract: Objectives Obesity is a serious global issue with a massive impact on the health and life of people worldwide. Besides being a neuropeptide, kisspeptin is an important adipokine involved in regulating energy homeostasis and body… read more here.

Keywords: adipokine obese; neuropeptide adipokine; kisspeptin act; kisspeptin ... See more keywords

Kisspeptin expression is decreased in the arcuate nucleus of hypothyroid female rats with irregular estrus cycles

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recommendations! Published in 2017 at "Neuroscience Research"

DOI: 10.1016/j.neures.2016.11.005

Abstract: Insufficiency of thyroid hormones inhibits gonadotropin release and results in dysregulation of reproductive function, although the precise mechanism of this disrupted gonadotropin secretion remains unclear. Kisspeptin is a neuropeptide that strongly stimulates gonadotropin secretion and… read more here.

Keywords: estrus cycles; arcuate nucleus; irregular estrus; expression ... See more keywords

Kisspeptin modulates pain sensitivity of CFLP mice

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recommendations! Published in 2018 at "Peptides"

DOI: 10.1016/j.peptides.2018.04.018

Abstract: HighlightsEffect of kisspeptin‐13 (KP‐13) on pain sensation was studied in male and female CFLP mice.KP‐13 reduces the pain threshold independent of the sex of mice in the tail‐flick test possibly through KISS1R activation.In addition, KP‐13… read more here.

Keywords: sensitivity; effect; cflp mice; mice ... See more keywords

Towards new strategies to manage livestock reproduction using kisspeptin analogs.

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recommendations! Published in 2018 at "Theriogenology"

DOI: 10.1016/j.theriogenology.2017.08.026

Abstract: The discovery of the hypothalamic neuropeptide kisspeptin and its receptor (KISS1R) have dramatically improved our knowledge about the central mechanisms controlling reproduction. Kisspeptin neurons could be considered the hub where internal and external information controlling… read more here.

Keywords: reproduction; controlling reproduction; new strategies; towards new ... See more keywords

Brainstem noradrenergic modulation of the kisspeptin neuron GnRH pulse generator in mice

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-60837-8

Abstract: Brainstem noradrenaline (NA) neurons modulate the activity of many neural networks including those responsible for the control of fertility. Using brain slice electrophysiology, we demonstrate that the arcuate nucleus kisspeptin (ARNKISS) neurons, recently identified to… read more here.

Keywords: gnrh pulse; brainstem; pulse generator; kisspeptin ... See more keywords

Triggering puberty in primates: is it NPY?

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recommendations! Published in 2022 at "Nature Reviews Endocrinology"

DOI: 10.1038/s41574-022-00673-8

Abstract: 0123456789();: Glutamate, γ-aminobutyric acid, neuropeptide Y (NPY) and kisspeptin have been pursued as central triggers of puberty in higher primates for many years. Since 2003, a lot of research has focused on the hypothalamic kisspeptinergic… read more here.

Keywords: triggering puberty; kisspeptin; puberty; primates npy ... See more keywords

Recombinant B2L and Kisspeptin-54 DNA Vaccine Induces Immunity Against Orf Virus and Inhibits Spermatogenesis In Rats

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recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-52744-y

Abstract: Orf is a highly contagious zoonotic disease of small ruminants caused by Parapoxvirus. Kisspeptin, encoded by the KISS1 gene with its cognate receptor GPR-54 is recognized as an upstream orchestrator in the hypothalamic-pituitary-gonadal axis. This… read more here.

Keywords: orf virus; kisspeptin; vaccine; b2l kisspeptin ... See more keywords