Arcuate Kisspeptin Neurons Coordinate Reproductive Activities with Metabolism.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in reproductive medicine"
DOI: 10.1055/s-0039-3400251
Abstract: Hypothalamic control of fertility is the quintessential homeostatic function. However, fertility is metabolically demanding; so, there must be coordination between energy states and reproductive functions. Because gonadotropin-releasing hormone (GnRH) neurons are devoid of many of… read more here.
Keywords: hormone; energy; gnrh neurons; kisspeptin neurons ... See more keywords
Transcriptome profiling of kisspeptin neurons from the mouse arcuate nucleus reveals new mechanisms in estrogenic control of fertility
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2113749119
Abstract: Significance The arcuate nucleus (ARC) of the mediobasal hypothalamus is critically involved in hormonal communication from ovary to brain. Negative estrogen feedback to kisspeptin synthesizing neurons of the ARC is a crucial determinant of hypothalamic… read more here.
Keywords: transcriptome profiling; kisspeptin; arcuate nucleus; fertility ... See more keywords
Impact of Perfluorooctane Sulfonate on Reproductive Ability of Female Mice through Suppression of Estrogen Receptor &agr;-Activated Kisspeptin Neurons
Sign Up to like & getrecommendations! Published in 2018 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfy167
Abstract: Perfluorooctane sulfonate (PFOS) is used extensively in industrial and household applications. High exposure to PFOS has been associated with increased odds of irregular and long menstrual cycles in women. However, the underlying mechanisms remain to… read more here.
Keywords: avpv kisspeptin; perfluorooctane sulfonate; pfos; kisspeptin neurons ... See more keywords
Pubertal Escape From Estradiol Negative Feedback in Ewe Lambs Is Not Accounted for by Decreased ESR1 mRNA or Protein in Kisspeptin Neurons
Sign Up to like & getrecommendations! Published in 2018 at "Endocrinology"
DOI: 10.1210/en.2017-00593
Abstract: In this study, we investigated whether decreased sensitivity to estradiol negative feedback is associated with reduced estrogen receptor α (ESR1) expression in kisspeptin neurons as ewe lambs approach puberty. Lambs were ovariectomized and received no… read more here.
Keywords: protein; kisspeptin neurons; esr1 mrna;
Stereology of gonadotropin-releasing hormone and kisspeptin neurons in PACAP gene-deficient female mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.993228
Abstract: The hypothalamic gonadotropin-releasing hormone (GnRH)–kisspeptin neuronal network regulates fertility in all mammals. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide isolated from the hypothalamus that is involved in the regulation of several releasing hormones and… read more here.
Keywords: gonadotropin releasing; kisspeptin; number; pacap ... See more keywords
The molecular phenotype of kisspeptin neurons in the medial amygdala of female mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1093592
Abstract: Reproduction is regulated through the hypothalamic-pituitary-gonadal (HPG) axis, largely via the action of kisspeptin neurons in the hypothalamus. Importantly, Kiss1 neurons have been identified in other brain regions, including the medial amygdala (MeA). Though the… read more here.
Keywords: kiss1 neurons; mea kiss1; kisspeptin neurons; medial amygdala ... See more keywords