Cardiac interstitial tetraploid cells can escape replicative senescence in rodents but not large mammals
Sign Up to like & getrecommendations! Published in 2019 at "Communications Biology"
DOI: 10.1038/s42003-019-0453-z
Abstract: Cardiomyocyte ploidy has been described but remains obscure in cardiac interstitial cells. Ploidy of c-kit+ cardiac interstitial cells was assessed using confocal, karyotypic, and flow cytometric technique. Notable differences were found between rodent (rat, mouse)… read more here.
Keywords: escape replicative; interstitial cells; cardiac interstitial; cells escape ... See more keywords
Reassessment of c-Kit in Cardiac Cells: A Complex Interplay Between Expression, Fate, and Function
Sign Up to like & getrecommendations! Published in 2018 at "Circulation Research"
DOI: 10.1161/circresaha.118.313215
Abstract: c-Kit (CD117) is a type III receptor tyrosine kinase that activates a downstream signaling cascade on binding to stem cell factor. Studies from the past 3 decades have demonstrated the expression of c-Kit in various… read more here.
Keywords: cardiac cells; adult; kit; kit cardiac ... See more keywords