GCT-19. MODELING GERM CELL TUMORS WITH KIT MUTANT hiPSCs
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.239
Abstract: Abstract Central Nervous System Germ Cell Tumor (CNS GCT) is the second most common pediatric brain tumor in Japan, and within CNS GCT, germinoma is the most common subtype, accounting for 62.3%. Recent reports of… read more here.
Keywords: kit mutant; germinoma; germ; germ cell ... See more keywords
A phase II study of binimetinib plus imatinib in patients with unresectable KIT-mutant melanoma.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.tps9605
Abstract: TPS9605 Background: Patients (pts) with melanoma refractory to immune checkpoint inhibition (ICI) remain in need of rational therapeutic options. Pts with rare melanoma subtypes (acral, mucosal) are in particular need given lower objective response rates… read more here.
Keywords: melanoma; response; phase study; kit mutant ... See more keywords