Synthesis, characterization, and in vitro cytotoxicity of a Kiteplatin-Ibuprofen Pt(IV) prodrug
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DOI: 10.1016/j.ica.2017.07.019
Abstract: Abstract The Pt(IV) prodrug of kiteplatin, cis-trans-cis-[PtCl2(RS-Ibuprofen-H)2(cis-1,4-DACH)], having in the axial positions two molecules of Ibuprofen, has been synthesised, characterized and tested in vitro. The aim was to potentiate the cytotoxic effect of kiteplatin with… read more here.
Keywords: anti inflammatory; kiteplatin; characterization vitro; vitro cytotoxicity ... See more keywords