A Novel Pyrazolo[3,4-d]pyrimidine Induces Heme Oxygenase-1 and Exerts Anti-Inflammatory and Neuroprotective Effects
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DOI: 10.14348/molcells.2021.0074
Abstract: The anti-oxidant enzyme heme oxygenase-1 (HO-1) is known to exert anti-inflammatory effects. From a library of pyrazolo[3,4-d]pyrimidines, we identified a novel compound KKC080096 that upregulated HO-1 at the mRNA and protein levels in microglial BV-2… read more here.
Keywords: kkc080096 upregulated; novel pyrazolo; pyrazolo pyrimidine; anti inflammatory ... See more keywords