High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1291
Abstract: Abstract The Cas9 nuclease from Staphylococcus aureus (SaCas9) holds great potential for use in gene therapy, and variants with increased fidelity have been engineered. However, we find that existing variants have not reached the greatest… read more here.
Keywords: fidelity; kkh; sacas9; staphylococcus aureus ... See more keywords
Epidemiology of stillbirths based on different gestational thresholds at a tertiary hospital.
Sign Up to like & getrecommendations! Published in 2022 at "Singapore medical journal"
DOI: 10.11622/smedj.2020173
Abstract: INTRODUCTION The stillbirth rate (SBR) is an important public health indicator. We studied the distribution of maternal and fetal characteristics and time trends of the SBR at KK Women's and Children's Hospital (KKH), Singapore, from… read more here.
Keywords: weeks weeks; kkh; 2004 2016; weeks gestation ... See more keywords