High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination
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DOI: 10.1093/nar/gkab1291
Abstract: Abstract The Cas9 nuclease from Staphylococcus aureus (SaCas9) holds great potential for use in gene therapy, and variants with increased fidelity have been engineered. However, we find that existing variants have not reached the greatest… read more here.
Keywords: fidelity; kkh; sacas9; staphylococcus aureus ... See more keywords