Comprehensive Mutational Analysis of the Lasso Peptide Klebsidin.
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DOI: 10.1021/acschembio.2c00148
Abstract: Antibiotic resistance is a growing threat to public health, making the development of antibiotics of critical importance. One promising class of potential new antibiotics are ribosomally synthesized and post-translationally modified peptides (RiPPs), which include klebsidin,… read more here.
Keywords: lasso peptide; analysis lasso; klebsidin; mutational analysis ... See more keywords
Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae.
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DOI: 10.1021/acschembio.6b01154
Abstract: We report the bioinformatic prediction and structural validation of two lasso peptides, acinetodin and klebsidin, encoded by the genomes of several human-associated strains of Acinetobacter and Klebsiella. Computation of the three-dimensional structures of these peptides… read more here.
Keywords: klebsiella; lasso peptides; klebsidin; rna polymerase ... See more keywords