Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites
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DOI: 10.1038/s41598-022-08645-8
Abstract: Endothelial cells (ECs) lining blood vessels are exposed to mechanical forces, such as shear stress. These forces control many aspects of EC biology, including vascular tone, cell migration and proliferation. Despite a good understanding of… read more here.
Keywords: transcription factor; shear stress; klf transcription; stress ... See more keywords
SP and KLF Transcription Factors in Cancer Metabolism
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DOI: 10.3390/ijms23179956
Abstract: Tumor development and progression depend on reprogramming of signaling pathways that regulate cell metabolism. Alterations to various metabolic pathways such as glycolysis, oxidative phosphorylation, lipid metabolism, and hexosamine biosynthesis pathway are crucial to sustain increased… read more here.
Keywords: klf transcription; factors cancer; metabolism; transcription ... See more keywords