3140 – A PROTEOMIC APPROACH TO IDENTIFY KLF1-REGULATED PROTEINS IN ERYTHROID ISLAND-LIKE MACROPHAGES
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DOI: 10.1016/j.exphem.2020.09.147
Abstract: Adult erythropoiesis is known to occur in the bone marrow where erythroid progenitors are produced from haematopoietic stem cells then proliferate, differentiate and mature into red blood cells prior entering the circulation. The later stages… read more here.
Keywords: proteomic approach; klf1; niche; identify klf1 ... See more keywords
Hemoglobin switching in mice carrying the Klf1Nan variant
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DOI: 10.3324/haematol.2019.239830
Abstract: Haploinsufficiency for transcription factor KLF1 causes a variety of human erythroid phenotypes, such as the In(Lu) blood type, increased HbA2 levels, and hereditary persistence of fetal hemoglobin. Severe dominant congenital dyserythropoietic anemia IV (CDA-IV) (OMIM… read more here.
Keywords: klf1nan; hemoglobin; klf1; klf1wt nan ... See more keywords