Silencing of the transcription factors Oct4, Sox2, Klf4, c-Myc or Nanog has different effect on teratoma growth.
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DOI: 10.1016/j.bbrc.2019.07.064
Abstract: Induced pluripotent stem cells (iPSC) have a great potential, but their clinical application depends on finding strategies to abolish their tumorigenic potential. The use of Oct4, Sox2, Klf4, c-Myc and Nanog to generate iPSC demonstrated… read more here.
Keywords: sox2 klf4; oct4 sox2; myc nanog; transcription factors ... See more keywords