Ketogenesis attenuates KLF5-dependent production of CXCL12 to overcome the immunosuppressive tumor microenvironment in colorectal cancer.
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DOI: 10.1158/0008-5472.can-21-2778
Abstract: The dynamic composition of the tumor microenvironment (TME) can markedly alter the response to targeted therapies for colorectal cancer (CRC). Cancer associated fibroblasts (CAF) are major components of TMEs that can direct and induce infiltration… read more here.
Keywords: ketogenesis; tme; tumor microenvironment; colorectal cancer ... See more keywords