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   Articles with "klf6" as a keyword



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MiR-181 enhances proliferative and migratory potentials of retinal endothelial cells in diabetic retinopathy by targeting KLF6.

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recommendations! Published in 2022 at "Current eye research"

DOI: 10.1080/02713683.2022.2039206

Abstract: PURPOSE We aimed to uncover the role of microRNA-181 (miR-181) in the disease onset of diabetic retinopathy (DR) and its underlying mechanism. METHODS MiR-181 levels in plasma and aqueous humor samples of non-proliferative diabetic retinopathy… read more here.

Keywords: mir 181; klf6; retinal endothelial; enhances proliferative ... See more keywords
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Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis

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recommendations! Published in 2020 at "Liver International"

DOI: 10.1111/liv.14542

Abstract: Primary sclerosing cholangitis (PSC) is characterized by chronic cholestasis and inflammation, which promotes cirrhosis and an increased risk of cholangiocellular carcinoma (CCA). The transcription factor Krueppel‐like‐factor‐6 (KLF6) is a mediator of liver regeneration, steatosis, and… read more here.

Keywords: fxr signalling; klf6 expression; primary sclerosing; klf6 ... See more keywords
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Inhibition of KLF6 reduces the inflammation and apoptosis of type II alveolar epithelial cells in acute lung injury.

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recommendations! Published in 2022 at "Allergologia et immunopathologia"

DOI: 10.15586/aei.v50i5.632

Abstract: BACKGROUND The development of acute lung injury (ALI) into a severe stage leads to acute respiratory distress syndrome (ARDS). The morbidity and mortality of ALI and ARDS are very high. Objective: This study is aimed… read more here.

Keywords: klf6; apoptosis; lps induced; alveolar epithelial ... See more keywords

KLF6 Induces Apoptosis in Human Lens Epithelial Cells Through the ATF4-ATF3-CHOP Axis

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recommendations! Published in 2020 at "Drug Design, Development and Therapy"

DOI: 10.2147/dddt.s218467

Abstract: Background Many studies have confirmed that high myopia is related to the high prevalence of cataracts, which results from apoptosis of lens epithelial cells (LECs) due to endoplasmic reticulum stress. Krüppel-like factor 6 (KLF6) is… read more here.

Keywords: klf6; apoptosis; atf4 atf3; atf3 chop ... See more keywords