Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis
Sign Up to like & getrecommendations! Published in 2020 at "Liver International"
DOI: 10.1111/liv.14542
Abstract: Primary sclerosing cholangitis (PSC) is characterized by chronic cholestasis and inflammation, which promotes cirrhosis and an increased risk of cholangiocellular carcinoma (CCA). The transcription factor Krueppel‐like‐factor‐6 (KLF6) is a mediator of liver regeneration, steatosis, and… read more here.
Keywords: fxr signalling; klf6 expression; primary sclerosing; klf6 ... See more keywords
Krüppel-Like Factor 6 Downregulation Is Connected with a Poor Prognosis and Tumor Growth in Non-Small-Cell Lung Cancer
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DOI: 10.1155/2022/3193553
Abstract: Purpose Research in this article was performed to explore the biological role and clinical significance of Krüppel-like transcription factor 6 (KLF6) in non-small-cell lung cancer (NSCLC). Methods KLF6 expression in NSCLC cell lines was analyzed… read more here.
Keywords: expression; nsclc; cell; klf6 expression ... See more keywords
Platelet derived TGF-β promotes cervical carcinoma cell growth by suppressing KLF6 expression
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DOI: 10.18632/oncotarget.19912
Abstract: Platelets in the primary tumor microenvironment play crucial roles in regulating tumor growth, metastasis, and angiogenesis, but the underlying mechanisms are unclear. Here, we show that platelet releasates exhibited a proliferative effect on HeLa cells,… read more here.
Keywords: hela cells; platelet; klf6 expression; platelet derived ... See more keywords