The Effect and Mechanism of KLF7 in the TLR4/NF-κB/IL-6 Inflammatory Signal Pathway of Adipocytes
Sign Up to like & getrecommendations! Published in 2018 at "Mediators of Inflammation"
DOI: 10.1155/2018/1756494
Abstract: Objective To investigate the role and possible molecular mechanism of Krüppel-like factor 7 (KLF7) in the TLR4/NF-κB/IL-6 inflammatory signaling pathway activated by free fatty acids (FFA). Methods The mRNA and protein expression levels of KLF7… read more here.
Keywords: tlr4 inflammatory; inflammatory signal; mechanism; klf7 ... See more keywords
Krüppel-Like Factor 7 is a Marker of Aggressive Gastric Cancer and Poor Prognosis
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000481748
Abstract: Background/Aims: Krüppel-like factor (KLF) 7 protein is a member of the KLF transcription factor family, which plays important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation and metabolism. However, the… read more here.
Keywords: like factor; gastric cancer; klf7; ppel like ... See more keywords
KLF7 Alleviates Atherosclerotic Lesions and Inhibits Glucose Metabolic Reprogramming in Macrophages by Regulating HDAC4/miR-148b-3p/NCOR1
Sign Up to like & getrecommendations! Published in 2022 at "Gerontology"
DOI: 10.1159/000524029
Abstract: Objectives: Atherosclerosis (AS) remains a major contributor to death worldwide. This study sought to explore the role of Krüppel-like factor 7 (KLF7) in AS lesions via regulating glucose metabolic reprogramming (GMR) in macrophages. Methods: AS… read more here.
Keywords: klf7; 148b ncor1; metabolic reprogramming; hdac4 ... See more keywords
DNA methylation of CpG sites in the chicken KLF7 promoter and Exon 2 in association with mRNA expression in abdominal adipose tissue and blood metabolic indicators
Sign Up to like & getrecommendations! Published in 2020 at "BMC Genetics"
DOI: 10.1186/s12863-020-00923-6
Abstract: Background Our previous study found that chicken KLF7 was an important regulator in formation of adipose tissue. In the present study, we analyzed the association for DNA methylation in chicken KLF7 with its transcripts of… read more here.
Keywords: methylation; klf7; klf7 transcripts; adipose tissue ... See more keywords
Effects of miR-132-3p on progress and epithelial mesenchymal transition of non-small cell lung cancer via regulating KLF7.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of thoracic disease"
DOI: 10.21037/jtd-21-353
Abstract: Background MicroRNAs (miRNAs) often appear as oncogenes or tumor suppressor genes. The aim of this research was to examine miR-132-3p and Kruppel-like factor 7 (KLF7) effects in the development of non-small cell lung cancer (NSCLC).… read more here.
Keywords: mir 132; tumor cells; klf7; cell ... See more keywords
KLF7 promotes macrophage activation by activating the NF-κB signaling pathway in epicardial adipose tissue in patients with coronary artery disease.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202006_21693
Abstract: OBJECTIVE Inflammatory accumulation in epicardial adipose tissue (EAT) may influence the formation and development of coronary artery disease (CAD). EAT macrophages exhibit M1 polarization and the secretion of a large number of inflammatory factors in… read more here.
Keywords: eat; klf7; adipose tissue; macrophage activation ... See more keywords
Krüppel-like Transcription Factor 7 Is a Causal Gene in Autism Development
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23063376
Abstract: Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disease. To date, more than 1000 genes have been shown to be associated with ASD, and only a few of these genes account for more than… read more here.
Keywords: klf7; autism; asd genes; transcription factor ... See more keywords
Molecular function of Krüppel-like factor 7 in biology.
Sign Up to like & getrecommendations! Published in 2023 at "Acta biochimica et biophysica Sinica"
DOI: 10.3724/abbs.2023061
Abstract: Krüppel-like factor 7 ( KLF7), also named ubiquitous KLF ( UKLF) based on its ubiquitous expression in adult human tissues, is a conserved gene in animals. There are few reports on KLF7 among KLFs; however,… read more here.
Keywords: klf7; function; development; like factor ... See more keywords