KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04059-8
Abstract: BACKGROUND Neurotoxicity induced by local anesthetics (LAs) is potentially life threatening, especially for patients with underlying diseases like diabetes. The anesthetic bupivacaine (Bup) has been reported to induce neurotoxicity mediated by reactive oxygen species (ROS),… read more here.
Keywords: klf9 regulates; hyperglycemia aggravated; expression; neurotoxicity ... See more keywords
KLF9 and KLF13 transcription factors boost myelin gene expression in oligodendrocytes as partners of SOX10 and MYRF
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac953
Abstract: Abstract Differentiated oligodendrocytes produce myelin and thereby ensure rapid nerve impulse conduction and efficient information processing in the vertebrate central nervous system. The Krüppel-like transcription factor KLF9 enhances oligodendrocyte differentiation in culture, but appears dispensable… read more here.
Keywords: klf9 klf13; sox10 myrf; transcription; gene ... See more keywords
Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14071737
Abstract: Simple Summary The nuclear protein Krüppel-like factor 9 (KLF9) suppresses development of cancers in multiple tissues including the liver. However, a mechanistic basis for how KLF9 decreases cancer initiation/development has not been elucidated. Here, we… read more here.
Keywords: klf9; stress inflammation; oxidative stress; ppel like ... See more keywords