Abstract 6569: KLIPP: Precision targeting of cancer with CRISPR
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-6569
Abstract: Current cancer therapeutic treatments are typically associated with significant collateral damage to normal tissues and the emergence of treatment resistance. Thus, there is an unmet need to develop therapies that are uniquely cancer specific and… read more here.
Keywords: cancer; cancer specific; klipp precision; precision targeting ... See more keywords
Abstract 6371: KLIPP: Precision targeting of fusions and amplified oncogenes using CRISPR
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-6371
Abstract: Oncogenic fusion genes and amplified oncogenes are common drivers of cancer but there are currently no therapeutic approaches available that directly target these cancer-specific genomic features. Amplified oncogenes in cancer can be found on chromosomes… read more here.
Keywords: fusions amplified; amplified oncogenes; cancer; klipp precision ... See more keywords