Scalable synthesis and structural characterization of reversible KLK6 inhibitors
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DOI: 10.1039/d2ra04670a
Abstract: Scalable asymmetric syntheses of two kallikrein-related protease 6 (KLK6) inhibitors are reported. The inhibitors are assembled by linking enantiomerically enriched fragments via amide bond formation, followed by conversion of a cyano group to an amidine.… read more here.
Keywords: characterization reversible; synthesis structural; klk6 inhibitors; scalable synthesis ... See more keywords