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   Articles with "klotho gene" as a keyword



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Klotho gene‐modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β‐catenin pathway in kidneys after acute injury

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recommendations! Published in 2018 at "Cell Biology International"

DOI: 10.1002/cbin.11068

Abstract: Klotho is a protein primarily expressed in renal tubular epithelial cells. Studies have suggested that Klotho is an antiaging protein that reduces renal fibrosis after acute kidney injury (AKI) and inhibits stem cell senescence. Bone… read more here.

Keywords: injury; bmscs; klotho gene; klotho gfp ... See more keywords
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Guanosine protects against glycerol-induced acute kidney injury via up-regulation of the klotho gene

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recommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"

DOI: 10.22038/ijbms.2022.60579.13428

Abstract: Objective(s): Acute Kidney Injury (AKI) is characterized by a rapid and reversible decline in renal function with a rapid decrease in Glomerular Filtration Rate (GFR), which is associated with high mortality. Rhabdomyolysis accounts for 10–40%… read more here.

Keywords: klotho gene; glycerol induced; guanosine; expression ... See more keywords
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The impact of SGLT2 inhibitors on αKlotho in renal MDCK and HK-2 cells

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recommendations! Published in 2023 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2023.1069715

Abstract: αKlotho is a transmembrane protein predominantly expressed in the kidney serving as a co-receptor for phosphate homeostasis-regulating hormone FGF23 and has an extracellular domain that can be cleaved off and is a hormone. αKlotho deficiency… read more here.

Keywords: klotho gene; mdck cells; inhibitors klotho; renal mdck ... See more keywords
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Association between KLOTHO Gene G395A Polymorphism and Carotid Artery Calcification in regular Hemodialysis Patients

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recommendations! Published in 2020 at "Open Access Macedonian Journal of Medical Sciences"

DOI: 10.3889/oamjms.2020.3790

Abstract: BACKGROUND: The vascular calcification process in chronic kidney disease (CKD) is a complication caused by mineral and bone abnormalities and becomes the risk of cardiovascular disease and mortality in CKD patients. KLOTHO is an inhibitor… read more here.

Keywords: klotho gene; gene g395a; carotid; calcification ... See more keywords