Evaluation of serum and aqueous humor klotho levels in pseudoexfoliation syndrome, pseudoexfoliation and primary open-angle glaucoma
Sign Up to like & getrecommendations! Published in 2021 at "International Ophthalmology"
DOI: 10.1007/s10792-021-01790-5
Abstract: The aim of our study was to compare klotho in the serum and aqueous humor of patients with primary open-angle glaucoma (POAG), pseudoexfoliation glaucoma (PEXG) and pseudoexfoliation syndrome (PEX). 18 POAG, 20 PEXG, 19 PEX… read more here.
Keywords: poag; aqueous humor; glaucoma; klotho levels ... See more keywords
Elevated Fibroblast Growth Factor 23 and Decreased Klotho Levels Are Associated With Diastolic Dysfunction in CKD G4–5D Patients
Sign Up to like & getrecommendations! Published in 2020 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2020.04.022
Abstract: To the Editor: In a recent study, Sharma et al. reported an association between higher levels of fibroblast growth factor 23 (FGF-23) and left ventricular (LV) diastolic dysfunction in 47 end-stage renal disease (ESRD) patients… read more here.
Keywords: fibroblast growth; growth factor; klotho levels; klotho ... See more keywords
Soluble klotho as an effective biomarker to characterize inflammatory states
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine"
DOI: 10.1080/07853890.2022.2077428
Abstract: Abstract Background & Aims Soluble α-Klotho (s-Klotho) is a circulating protein with pleiotropic effects that mainly induce protective effects. Our study investigates the associations between s-Klotho and several established inflammatory biomarkers, with the aim of… read more here.
Keywords: inflammatory biomarkers; biomarker; inflammatory states; klotho ... See more keywords
Association between Serum α-Klotho Levels and Behçet Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac146
Abstract: BACKGROUND Endothelial dysfunction (ED) has a well-known role in promoting vascular inflammation in Behçet disease (BD). α-klotho is involved in regulation of endothelial function, and its reduction has been reported to be associated with ED.… read more here.
Keywords: beh disease; serum klotho; klotho; klotho levels ... See more keywords
The association of soluble Klotho levels with anemia and hemoglobin variability in hemodialysis patients
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in Dialysis"
DOI: 10.1111/sdi.13122
Abstract: The anti‐aging protein Klotho levels are decreased, and Klotho deficiency is associated with cardiovascular diseases in patients with chronic kidney disease. There are recent studies about the relation between soluble Klotho levels and anemia. We… read more here.
Keywords: hemoglobin variability; klotho; anemia hemoglobin; soluble klotho ... See more keywords
The Association of Obesity and the Antiaging Humoral Factor Klotho in Middle-Aged and Older Adults
Sign Up to like & getrecommendations! Published in 2022 at "The Scientific World Journal"
DOI: 10.1155/2022/7274858
Abstract: Objectives Previous studies have reported conflicting results regarding the relationship between obesity and the antiaging humoral factor klotho. Thus, the present study aimed to examine the association of anthropometric measurements, weight history change, and vitamin… read more here.
Keywords: obesity; serum klotho; klotho levels; obesity antiaging ... See more keywords
Composite Dietary Antioxidant Index and Plasma Levels of Soluble Klotho: Insights from NHANES
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/3524611
Abstract: Objectives The association between dietary antioxidants and soluble Klotho (S-Klotho) levels remains unknown. We investigated to explore whether the composite dietary antioxidant index (CDAI) was associated with serum levels of S-Klotho in the middle-aged population.… read more here.
Keywords: index; klotho; plasma; composite dietary ... See more keywords
Circulating α-Klotho Levels in Relation to Cardiovascular Diseases: A Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.842846
Abstract: Background Several studies have reported a protective role of circulating α-Klotho on cardiovascular diseases (CVD); however, the causality remains unclear. We aim to elucidate whether genetically predicted circulating α-Klotho levels were causally associated with the… read more here.
Keywords: mendelian randomization; cardiovascular diseases; klotho; randomization study ... See more keywords
Reduced Plasma Levels of α-Klotho and Their Correlation With Klotho Polymorphisms in Elderly Patients With Major Depressive Disorders
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.682691
Abstract: Background: Recent literature suggests that α-Klotho, a widely recognized anti-aging protein, is involved in longevity as well as in many diseases, including Alzheimer's disease, and depression. Although the Klotho gene encodes α-Klotho, a single transmembrane… read more here.
Keywords: mdd patients; plasma klotho; mdd; age ... See more keywords