Articles with "kltg mice" as a keyword



FGF23 expression is stimulated in transgenic α-Klotho longevity mouse model.

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Published in 2019 at "JCI insight"

DOI: 10.1172/jci.insight.132820

Abstract: Observations in transgenic α-Klotho (Kl) mice (KlTg) defined the antiaging role of soluble Klotho (sKL130). A genetic translocation that elevates sKL levels in humans is paradoxically associated with increased circulating fibroblast growth factor 23 (FGF23)… read more here.

Keywords: kltg mice; transgenic klotho; expression; fgf23 expression ... See more keywords