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Published in 2020 at "Pakistan Veterinary Journal"
DOI: 10.29261/pakvetj/2020.012
Abstract: Received: Revised: Accepted: Published online: July 28, 2019 January 05, 2020 January 09, 2020 February 03, 2020 Kynurenine 3-monooxygenase (KMO), an outer mitochondrial membrane enzyme that is central to the kynurenine pathway, has been demonstrated…
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Keywords:
sf9 cells;
canine;
kynurenine monooxygenase;
baculovirus ... See more keywords
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Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11020315
Abstract: Kynurenine 3-monooxygenase (KMO), a key player in the kynurenine pathway (KP) of tryptophan degradation, regulates the synthesis of the neuroactive metabolites 3-hydroxykynurenine (3-HK) and kynurenic acid (KYNA). KMO activity has been implicated in several major…
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Keywords:
kynurenine monooxygenase;
kmo activity;
kmo;
brain ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27010273
Abstract: Under normal physiological conditions, the kynurenine pathway (KP) plays a critical role in generating cellular energy and catabolizing tryptophan. Under inflammatory conditions, however, there is an upregulation of the KP enzymes, particularly kynurenine 3-monooxygenase (KMO).…
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Keywords:
kynurenine pathway;
kynurenine monooxygenase;
pathway kynurenine;
monooxygenase inhibitors ... See more keywords