Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
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DOI: 10.1002/ijc.35332
Abstract: Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation… read more here.
Keywords: lessons learned; menin kmt2a; leukemia; kmt2a interaction ... See more keywords