Articles with "kmt2a leukemia" as a keyword



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Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.779859

Abstract: Patients whose leukemias harbor a rearrangement of the Mixed Lineage Leukemia (MLL/KMT2A) gene have a poor prognosis, especially when the disease strikes in infants. The poor clinical outcome linked to this aggressive disease and the… read more here.

Keywords: leukemia cell; novel candidate; leukemia; kmt2a leukemia ... See more keywords