Articles with "kmt2c lof" as a keyword



Association of KMT2C/D loss‐of‐function variants with response to immune checkpoint blockades in colorectal cancer

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Published in 2023 at "Cancer Science"

DOI: 10.1111/cas.15716

Abstract: Immune checkpoint inhibitors (ICIs) have become important treatment strategies, yet responses vary among patients and predictive biomarkers are urgently needed. Mutations in KMT2C and KMT2D lead to increased levels of genomic instability. Therefore, we aimed… read more here.

Keywords: lof variants; kmt2c lof; colorectal cancer; association ... See more keywords