Effect of Pulsed Low-Intensity Ultrasonography on Symptom Relief and Tibiofemoral Articular Cartilage Thickness Among Veterans Affairs Enrollees With Knee Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.0632
Abstract: Key Points Question Does 48 weeks of pulsed low-intensity ultrasonography (PLIUS) provide therapeutic benefit for patients with idiopathic knee osteoarthritis? Findings In this randomized clinical trial of 132 adults with symptomatic and radiographic idiopathic knee… read more here.
Keywords: intensity ultrasonography; cartilage thickness; cartilage; low intensity ... See more keywords
Nuclear binding SET domain 1 alleviates cartilage ferroptosis in knee osteoarthritis by upregulating the krüppel‐like factor 9/autophagy‐related 14 pathway via H3K36me2 modification
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cell Communication and Signaling"
DOI: 10.1002/ccs3.70027
Abstract: Knee osteoarthritis (KOA) is a progressive disease featured by cartilage damage. This study attempts to explore the role of nuclear binding SET domain 1 (NSD1) in KOA cartilage ferroptosis, thereby finding a new target for… read more here.
Keywords: knee osteoarthritis; ferroptosis; klf9; cartilage ferroptosis ... See more keywords
Movement‐evoked pain is not associated with pain at rest or physical function in knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Pain"
DOI: 10.1002/ejp.2236
Abstract: Knee Osteoarthritis (KOA) is mainly characterized by pain. The assessment of KOA‐related pain frequently focuses on different constructs subject to sources of bias or drawbacks, as the classical Pain at Rest (PAR). Movement‐evoked pain (MEP),… read more here.
Keywords: evoked pain; knee osteoarthritis; pain; pain rest ... See more keywords
Automated knee osteoarthritis severity classification using three‐stage preprocessing method and VGG16 architecture
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Imaging Systems and Technology"
DOI: 10.1002/ima.22845
Abstract: As a nutshell, an early diagnosis of Knee Osteoarthritis (KOA) enhances the likelihood of an individual receiving treatment at its onset and prevents joint replacement surgery. Computer‐Aided‐Diagnosis (CAD) from the radiograph images have gained a… read more here.
Keywords: classification; vgg16 architecture; severity; knee osteoarthritis ... See more keywords
Automatic detection of knee osteoarthritis grading using artificial intelligence‐based methods
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Imaging Systems and Technology"
DOI: 10.1002/ima.23057
Abstract: Osteoarthritis (OA) means that the slippery cartilage tissue that covers the bone surfaces in the joints and allows the joint to move easily loses its properties and wears out. Knee OA is the wear and… read more here.
Keywords: knee osteoarthritis; osteoarthritis grading; automatic detection; knee ... See more keywords
Change of miRNA expression profiles in patients with knee osteoarthritis before and after celecoxib treatment
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22648
Abstract: This study aimed to investigate the change of circulating miRNA expression profiles in knee osteoarthritis (OA) patients before and after celecoxib treatment. read more here.
Keywords: expression profiles; change; knee osteoarthritis; celecoxib treatment ... See more keywords
Diagnostic accuracy of a novel ultrasound imaging index for knee osteoarthritis: Evaluation of sensitivity, specificity, and predictive values
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23691
Abstract: We aimed to develop and validate a new ultrasonography (US) index for the diagnosis of primary medial‐type knee osteoarthritis (OA). read more here.
Keywords: knee osteoarthritis; index; novel ultrasound; accuracy novel ... See more keywords
BMI‐related microstructural changes in the tibial subchondral trabecular bone of patients with knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23459
Abstract: Overweight is a risk factor for osteoarthritis on the knees. Subchondral trabecular bone (SCTB) densification has been shown to be associated with cartilage degeneration. This study analyzed the microarchitectural changes in the SCTB of tibial… read more here.
Keywords: knee osteoarthritis; bone; trabecular bone; subchondral trabecular ... See more keywords
Baseline knee adduction moment interacts with body mass index to predict loss of medial tibial cartilage volume over 2.5 years in knee Osteoarthritis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23564
Abstract: This study aimed to determine the extent to which changes over 2.5 years in medial knee cartilage thickness and volume were predicted by: (1) Peak values of the knee adduction (KAM) and flexion moments; and… read more here.
Keywords: volume; knee osteoarthritis; cartilage; cartilage volume ... See more keywords
On Patient Quality of Life: Impacts of Knee Osteoarthritis on Pain, Anxiety, Depression, Fatigue and Sleep Disorders
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DOI: 10.1002/nop2.70264
Abstract: Patients repeatedly experiencing a sustained disease course, recurrent chronic pain, and serious sleep disorder will weaken their physical resistance and self‐care ability. Further evidence on patients with knee osteoarthritis (KOA) and related latent classes (LCs)… read more here.
Keywords: patient quality; knee osteoarthritis; life impacts; pain ... See more keywords
Identification and quantification of degradome components in human synovial fluid reveals an increased proteolytic activity in knee osteoarthritis patients vs controls.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202300040
Abstract: Synovial fluid (SF) may contain cleavage products of proteolytic activities. Our aim was to characterize the degradome through analysis of proteolytic activity and differential abundance of these components in a peptidomic analysis of SF in… read more here.
Keywords: osteoarthritis patients; knee osteoarthritis; activity; knee ... See more keywords