Accelerating Sequence Alignments Based on FM-Index Using the Intel KNL Processor
Sign Up to like & getrecommendations! Published in 2020 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2018.2884701
Abstract: FM-index is a compact data structure suitable for fast matches of short reads to large reference genomes. The matching algorithm using this index exhibits irregular memory access patterns that cause frequent cache misses, resulting in… read more here.
Keywords: intel; accelerating sequence; sequence alignments; memory ... See more keywords
Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.259088
Abstract: Centromeres are chromosomal regions that serve as sites for kinetochore formation and microtubule attachment, processes that are essential for chromosome segregation during mitosis. Centromeres are almost universally defined by the histone variant CENP-A. In the… read more here.
Keywords: chromosome condensation; knl; cenp; phosphorylation ... See more keywords