The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007761
Abstract: Plasmodium falciparum mediates adhesion of infected red blood cells (RBCs) to blood vessel walls by assembling a multi-protein complex at the RBC surface. This virulence-mediating structure, called the knob, acts as a scaffold for the… read more here.
Keywords: microscopy; virulence; knob; structure ... See more keywords
[Educating to properly close the toilet knob taps or to replace them].
Sign Up to like & getrecommendations! Published in 2020 at "Epidemiologia e prevenzione"
DOI: 10.19191/ep20.5-6.s2.091
Abstract: Systematic reviews have shown a prevalence close to 20% of gastrointestinal symptoms in COVID-19 positive patients, with nearly 40% of patients shedding viral RNA in their faeces, even if it may not be infectious, possibly… read more here.
Keywords: educating properly; knob; knob taps; properly close ... See more keywords
Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1170357
Abstract: Background Serum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody… read more here.
Keywords: serum albumin; albumin binding; knob domains; framework iii ... See more keywords
CELO Fiber1 Knob Is a Promising Candidate to Modify the Tropism of Adenoviral Vectors
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13122316
Abstract: Fowl adenovirus 4 (FAdV-4) has the potential to be constructed as a gene transfer vector for human gene therapy or vaccine development to avoid the pre-existing immunity to human adenoviruses. To enhance the transduction of… read more here.
Keywords: fiber1 knob; celo fiber1; cf1k; tropism ... See more keywords