Articles with "knob domains" as a keyword



Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1170357

Abstract: Background Serum albumin binding is an established mechanism to extend the serum half-life of antibody fragments and peptides. The cysteine rich knob domains, isolated from bovine antibody ultralong CDRH3, are the smallest single chain antibody… read more here.

Keywords: serum albumin; albumin binding; knob domains; framework iii ... See more keywords