Abstract 5097: Knock-in of a human tumor suppressor (25-kilobase pairs) by traditional and CRISPR/Cas9-stimulated homologous recombination
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DOI: 10.1158/1538-7445.am2018-5097
Abstract: Here we describe an expansion of the DNA size limitations associated with CRISPR knock-in technology, more specifically, the physical extent to which mouse genomic DNA can be replaced with donor (in this case, human) DNA… read more here.
Keywords: tumor suppressor; human tumor; knock human; tumor ... See more keywords