Allele-Specific RNA Knockdown with a Biologically Stable and Catalytically Efficient XNAzyme.
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DOI: 10.1021/jacs.0c11353
Abstract: Therapeutic targeting of allele-specific single nucleotide mutations in RNA is a major challenge in biology and medicine. Herein, we describe the utility of the XNAzyme X10-23 to knock down allele-specific mRNA sequences in cells. We… read more here.
Keywords: specific rna; xnazyme; knockdown biologically; rna knockdown ... See more keywords