Articles with "knockdown hbs1l" as a keyword



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Induction of fetal hemoglobin: Lentiviral shRNA knockdown of HBS1L in β0-thalassemia/HbE erythroid cells

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Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0281059

Abstract: Imbalanced globin chain output contributes to thalassemia pathophysiology. Hence, induction of fetal hemoglobin in β-thalassemia and other β-hemoglobinopathies are of continuing interest for therapeutic approaches. Genome-wide association studies have identified three common genetic loci: namely… read more here.

Keywords: induction fetal; fetal hemoglobin; thalassemia hbe; knockdown hbs1l ... See more keywords