Knocking 'em Dead: Pore-Forming Proteins in Immune Defense.
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DOI: 10.1146/annurev-immunol-111319-023800
Abstract: Immune cells use a variety of membrane-disrupting proteins [complement, perforin, perforin-2, granulysin, gasdermins, mixed lineage kinase domain-like pseudokinase (MLKL)] to induce different kinds of death of microbes and host cells, some of which cause inflammation.… read more here.
Keywords: dead pore; knocking dead; pore forming; forming proteins ... See more keywords