cyp21a2 knockout tadpoles survive metamorphosis despite low corticosterone.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac182
Abstract: Corticosteroids are vital for organ maturation such that reduced corticosteroid signaling during post-embryonic development causes death in terrestrial vertebrates. Indeed, death occurs at metamorphosis in frogs lacking proopiomelanocortin (pomc) or the glucocorticoid receptor (GR; nr3c1).… read more here.
Keywords: metamorphosis; corticosteroid signaling; cyp21a2; knockout tadpoles ... See more keywords