Knockout of TIGAR enhances myocardial phosphofructokinase activity and preserves diastolic function in heart failure
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DOI: 10.1002/jcp.30790
Abstract: Hypertension is an important risk factor in the pathogenesis of diastolic dysfunction. Growing evidence indicates that glucose metabolism plays an essential role in diastolic dysfunction. TP53‐induced glycolysis and apoptosis regulator (TIGAR) has been shown to… read more here.
Keywords: tigar; heart failure; knockout tigar; diastolic dysfunction ... See more keywords