Plasmodium knowlesi detection methods for human infections-Diagnosis and surveillance.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in parasitology"
DOI: 10.1016/bs.apar.2021.08.002
Abstract: Within the overlapping geographical ranges of P. knowlesi monkey hosts and vectors in Southeast Asia, an estimated 1.5 billion people are considered at risk of infection. P. knowlesi can cause severe disease and death, the… read more here.
Keywords: knowlesi; surveillance; diagnosis; knowlesi detection ... See more keywords
Molecular epidemiology and population genomics of Plasmodium knowlesi.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in parasitology"
DOI: 10.1016/bs.apar.2021.08.003
Abstract: Molecular epidemiology has been central to uncovering P. knowlesi as an important cause of human malaria in Southeast Asia, and to understanding the complex nature of this zoonosis. Species-specific parasite detection and characterization of sequences… read more here.
Keywords: knowlesi; epidemiology population; population genomics; epidemiology ... See more keywords
Infection of mosquitoes from in vitro cultivated Plasmodium knowlesi H strain.
Sign Up to like & getrecommendations! Published in 2018 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2018.02.004
Abstract: In vitro studies of sexual blood stages of the most fatal malaria species, Plasmodium falciparum, have revealed key processes by which gametocytes develop and transmit infection from humans to anopheline mosquitoes. However, most malaria cases… read more here.
Keywords: knowlesi; mosquitoes vitro; plasmodium knowlesi; vitro cultivated ... See more keywords
The Plasmodium knowlesi MAHRP2 ortholog localizes to structures connecting Sinton Mulligan's clefts in the infected erythrocyte.
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology international"
DOI: 10.1016/j.parint.2018.04.005
Abstract: During development within the host erythrocyte malaria parasites generate nascent membranous structures which serve as a pathway for parasite protein transport to modify the host cell. The molecular basis of such membranous structures is not… read more here.
Keywords: mulligan clefts; knowlesi; sinton mulligan; plasmodium knowlesi ... See more keywords
The Treatment of Plasmodium knowlesi Malaria.
Sign Up to like & getrecommendations! Published in 2017 at "Trends in parasitology"
DOI: 10.1016/j.pt.2016.09.002
Abstract: Plasmodium knowlesi occurs across Southeast Asia and is the most common cause of malaria in Malaysia. High parasitaemias can develop rapidly, and the risk of severe disease in adults is at least as high as… read more here.
Keywords: treatment; knowlesi malaria; knowlesi; plasmodium knowlesi ... See more keywords
Cation ATPase (ATP4) Orthologue Replacement in the Malaria Parasite Plasmodium knowlesi Reveals Species-Specific Responses to ATP4-Targeting Drugs
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01178-22
Abstract: Effective drugs are vital to minimize the illness and death caused by malaria. Development of new drugs becomes ever more urgent as drug resistance emerges. ABSTRACT Several unrelated classes of antimalarial compounds developed against Plasmodium… read more here.
Keywords: malaria parasite; plasmodium; atp4; susceptibility ... See more keywords
Developing a Predictive Model for Plasmodium knowlesi-Susceptible Areas in Malaysia Using Geospatial Data and Artificial Neural Networks.
Sign Up to like & getrecommendations! Published in 2021 at "Asia-Pacific journal of public health"
DOI: 10.1177/10105395211048620
Abstract: Plasmodium knowlesi is an emerging species for malaria in Malaysia, particularly in East Malaysia. This infection contributes to almost half of all malaria cases and deaths in Malaysia and poses a challenge in eradicating malaria.… read more here.
Keywords: knowlesi; malaria cases; predictive model; plasmodium knowlesi ... See more keywords
Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models
Sign Up to like & getrecommendations! Published in 2020 at "Malaria Journal"
DOI: 10.1186/s12936-020-03385-4
Abstract: Background Rhesus macaques are valuable pre-clinical models for malaria vaccine development. The Plasmodium knowlesi/rhesus and Plasmodium falciparum/rhesus models are two established platforms for malaria vaccine testing, and both have previously been used to assess live-attenuated… read more here.
Keywords: 18s rrna; knowlesi; rhesus; falciparum ... See more keywords
Reduced circulating dendritic cells in acute Plasmodium knowlesi and Plasmodium falciparum malaria despite elevated plasma Flt3 ligand levels
Sign Up to like & getrecommendations! Published in 2021 at "Malaria Journal"
DOI: 10.1186/s12936-021-03642-0
Abstract: Background Plasmodium falciparum malaria increases plasma levels of the cytokine Fms-like tyrosine kinase 3 ligand (Flt3L), a haematopoietic factor associated with dendritic cell (DC) expansion. It is unknown if the zoonotic parasite Plasmodium knowlesi impacts… read more here.
Keywords: knowlesi; malaria; plasmodium knowlesi; plasmodium falciparum ... See more keywords
Renal detection of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in malaria associated acute kidney injury: a retrospective case–control study
Sign Up to like & getrecommendations! Published in 2020 at "BMC Research Notes"
DOI: 10.1186/s13104-020-4900-1
Abstract: Acute kidney injury (AKI) is a frequent presentation in malaria infections. Several cases of AKI that are accompanied by clinical symptoms of malaria infection, such as fever, nausea, respiratory distress, and anemia remain undiagnosed due… read more here.
Keywords: knowlesi; malaria associated; vivax; plasmodium ... See more keywords
Malaria elimination in Malaysia and the rising threat of Plasmodium knowlesi
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physiological Anthropology"
DOI: 10.1186/s40101-020-00247-5
Abstract: Background Malaria is a major public-health problem, with over 40% of the world’s population (more than 3.3 billion people) at risk from the disease. Malaysia has committed to eliminate indigenous human malaria transmission by 2020.… read more here.
Keywords: knowlesi; malaria; malaysia; malaria elimination ... See more keywords