Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria
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DOI: 10.1016/j.ekir.2021.01.029
Abstract: Introduction Primary hyperoxaluria (PH) is a family of 3 rare genetic disorders of hepatic glyoxylate metabolism that lead to overproduction and increased renal excretion of oxalate resulting in progressive renal damage. LDHA inhibition of glyoxylate-to-oxalate… read more here.
Keywords: primary hyperoxaluria; rna interference; known types; ldha inhibition ... See more keywords