Amending Koch's postulates for viral disease: When “growth in pure culture” leads to a loss of virulence
Sign Up to like & getrecommendations! Published in 2017 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2016.11.002
Abstract: Abstract It is a common laboratory practice to propagate viruses in cell culture. While convenient, these methodologies often result in unintentional genetic alterations, which have led to adaptation and even attenuation in animal models of… read more here.
Keywords: amending koch; disease; koch postulates; postulates viral ... See more keywords
Commensal Koch's postulates: establishing causation in human microbiota research.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in microbiology"
DOI: 10.1016/j.mib.2017.10.001
Abstract: Advances in high-throughput sequencing technologies and the development of sophisticated bioinformatics analysis methods, algorithms, and pipelines to handle the large amounts of data generated have driven the field of human microbiome research forward. This specialist… read more here.
Keywords: research; microbiota; human gut; commensal ... See more keywords