Antinociceptive Effects of Kappa-Opioid Receptor Agonists.
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DOI: 10.1007/164_2020_430
Abstract: Preclinical models that assess "pain" in rodents typically measure increases in behaviors produced by a "pain stimulus." A large literature exists showing that kappa opioid receptor (KOR) agonists can decrease these "pain-stimulated behaviors" following many… read more here.
Keywords: kor agonists; opioid receptor; pain; kappa opioid ... See more keywords
The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.837671
Abstract: Kappa-opioid receptors (KOR) are widely expressed throughout the central nervous system, where they modulate a range of physiological processes depending on their location, including stress, mood, reward, pain, inflammation, and remyelination. However, clinical use of… read more here.
Keywords: promising therapeutic; opioid receptor; kappa opioid; development ... See more keywords