Articles with "kpf" as a keyword



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Kaempferol‐loaded mucoadhesive nanoemulsion for intranasal administration reduces glioma growth in vitro

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Published in 2018 at "International Journal of Pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.03.055

Abstract: &NA; In order to search for new approaches to treat glioma, intranasal administration has been proposed as an alternative route to deliver drugs into the brain. Among the drug alternatives, kaempferol (KPF) has been reported… read more here.

Keywords: intranasal administration; kpf; mucoadhesive nanoemulsion; kpf mne ... See more keywords
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Validation of an HPLC‐UV method for analysis of Kaempferol‐loaded nanoemulsion and its application to in vitro and in vivo tests

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Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2017.07.046

Abstract: HighlightsA validation of an HPLC‐UV method to determine KPF in different matrices.The method is applicable to quantification of KPF in nanotechnology‐based product.First validated method to assay KPF after mucosa permeation and brain delivery.The validated method… read more here.

Keywords: vivo; kaempferol; method; kpf ... See more keywords
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Amelioration effects of Kaempferol on immune response following chronic intermittent cold-stress.

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Published in 2019 at "Research in veterinary science"

DOI: 10.1016/j.rvsc.2019.08.012

Abstract: Cold-stress causes disturbance of the homeostatic regulation of animals, and gradually impairs the immune and antioxidant functions of animals. Therefore, increasing the effectiveness of the immune response and antioxidant function are the most attractive strategies… read more here.

Keywords: kpf; stress; blood; immune response ... See more keywords
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Protective Effect of Kaempferol and Its Nanoparticles on 5-Fluorouracil-Induced Cardiotoxicity in Rats

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Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/2273000

Abstract: Background Fluorouracil (5-FU) is the third most common chemotherapeutic agent used in the treatment of solid tumors. 5-FU-associated cardiotoxicity ranks the second causes of cardiotoxicity induced by chemotherapeutic drugs after anthracyclines. Kaempferol (KPF), a common… read more here.

Keywords: induced cardiotoxicity; kpf; kpf kpf; cardiotoxicity ... See more keywords
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Kaempferol attenuated diabetic nephropathy by reducing apoptosis and promoting autophagy through AMPK/mTOR pathways

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Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.986825

Abstract: Introduction Renal podocyte injury, apoptosis and autophagy are involved in the occurrence and development of diabetic nephropathy (DN). Kaempferol (KPF) has the promotion of autophagy and inhibition of apoptosis properties in the development of miscellaneous… read more here.

Keywords: apoptosis; kpf; ampk mtor; autophagy ampk ... See more keywords