Sequence-Based Genomic Analysis Reveals Transmission of Antibiotic Resistance and Virulence among Carbapenemase-Producing Klebsiella pneumoniae Strains
Sign Up to like & getrecommendations! Published in 2022 at "mSphere"
DOI: 10.1128/msphere.00143-22
Abstract: In this study, we combined genomic and epidemiological analyses and defined an optimal cutoff value for SNP difference that could be used to aid investigation in tertiary hospital in China. We revealed clonal transmission was… read more here.
Keywords: virulence genes; transmission; plasmids carrying; virulence ... See more keywords
Klebsiella pneumoniae infection of murine neutrophils impairs their efferocytic clearance by modulating cell death machinery
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DOI: 10.1371/journal.ppat.1007338
Abstract: Neutrophils are the first infiltrating cell type essential for combating pneumoseptic infections by bacterial pathogens including Klebsiella pneumoniae (KPn). Following an infection or injury, removal of apoptotic infiltrates via a highly regulated process called efferocytosis… read more here.
Keywords: cell; kpn; infection; cell death ... See more keywords
Identification and Evaluation of Recombinant Outer Membrane Proteins as Vaccine Candidates Against Klebsiella pneumoniae
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DOI: 10.3389/fimmu.2021.730116
Abstract: Klebsiella pneumoniae found in the normal flora of the human oral and intestinal tract mainly causes hospital-acquired infections but can also cause community-acquired infections. To date, most clinical trials of vaccines against K. pneumoniae have… read more here.
Keywords: klebsiella pneumoniae; outer membrane; kpn; membrane proteins ... See more keywords
Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures
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DOI: 10.3390/biom11040595
Abstract: Galectins bind various pathogens through recognition of distinct carbohydrate structures. In this work, we examined the binding of four human galectins to the Gram-negative bacteria Klebsiella pneumoniae (Kpn) and non-typeable Haemophilus influenzae (NTHi), which display… read more here.
Keywords: chain; kpn; galectin ligands; gram negative ... See more keywords
Suppression of Kpnβ1 expression inhibits human breast cancer cell proliferation by abrogating nuclear transport of Her2
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DOI: 10.3892/or.2017.6151
Abstract: Breast cancer (BC) is one of the most fatal diseases and poses critical health problems worldwide. However, its mechanisms remain unclear. Consequently, there is an urgency to investigate the mechanisms involved in BC initiation and… read more here.
Keywords: kpn; cell proliferation; breast cancer; expression ... See more keywords